HIGHLIGHTS
- who: Kaipeng Jin and collaborators from the University of Hail, Saudi Arabia have published the Article: Cyclooxygenase-2-Prostaglandin E2 pathway: A key player in tumor-associated immune cells, in the Journal: (JOURNAL)
- future: It may be debatable how EP3 contributes to carcinogenesis and more research is required. More clinical trials and studies are required to explore this further. Although there is abundant EP receptor expression in fibroblasts and inflammatory cells the role of the COX-2-PGE2 signaling pathway in TME is not fully understood and more studies are needed to demonstrate this.
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