Cyclooxygenase-2 upregulated by temozolomide in glioblastoma cells is shuttled in extracellular vesicles modifying recipient cell phenotype

HIGHLIGHTS

• who: Francesca Lombardi et al. from the Department of Life, Health and Environmental Sciences, University of L`Aquila, L`Aquila, Italy, Department of Medicine and have published the research work: Cyclooxygenase-2 Upregulated by Temozolomide in Glioblastoma Cells Is Shuttled In Extracellular Vesicles Modifying Recipient Cell Phenotype, in the Journal: (JOURNAL)
• what: The authors show evidence that low and clinically relevant TMZ concentrations, able to upmodulate COX-2 in T98G and U87MG cells, led to a dose-dependent increase of the COX-2 levels in secreted EV.
• how: Data were analyzed with the . . .
  

   

  

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