Cyclophilin a enables specific hiv-1 tat palmitoylation and accumulation in uninfected cells

HIGHLIGHTS

• who: Christophe Chopard from the CNRS de Strasbourg, Strasbourg, France, INSERM, Paris , France. have published the Article: Cyclophilin A enables specific HIV-1 Tat palmitoylation and accumulation in uninfected cells, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: In the search for cell proteins that might regulate Tat palmitoylation, the authors focused on prolylisomerases, i.e., proteins of the immunophilin family34.
• how: The results showed that transfected Tat-C31S displayed native Tat transactivation capacity (Supplementary Fig 1) indicating that the C31S mutation does not affect Tat structure and reactivity. Similar results were obtained . . .
  

   

  

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