HIGHLIGHTS
- who: Yi-Ming Chen from the Agostino Gemelli University Polyclinic (IRCCS), Italy have published the research: CYP2C19 loss-of-function alleles predicts clinical outcomes in East Asian patients with acute myocardial infarction undergoing percutaneous coronary intervention and stenting receiving clopidogrel, in the Journal: (JOURNAL)
- what: All these studies highlighted the crucial rule of CYP2C19 LOF alleles the study had several limitations. Fourth, although the study demonstrated that CYP2C19 PM were associated with high 1year MACCE in AMI, large-scale studies are still warranted to find the pragmatic approach in clinical practice of genotypeguided de-escalation . . .

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