Cysteamine re-establishes the clearance of pseudomonas aeruginosa by macrophages bearing the cystic fibrosis-relevant f508del-cftr mutation

HIGHLIGHTS

  • who: Eleonora Ferrari from the DivisionUniversity of Piemonte Orientale, Novara, Italy have published the paper: Cysteamine re-establishes the clearance of Pseudomonas aeruginosa by macrophages bearing the cystic fibrosis-relevant F508del-CFTR mutation, in the Journal: (JOURNAL)
  • what: The authors show that cysteamine can restore the impaired ability of CFTR defective macrophages in killing P. aeruginosa through restoring BECN1 expression and autophagy.
  • how: Data were analyzed using SPSS 20 software.
  • future: The results offer a new perspective for the treatment of P. aeruginosa infection in CF patients as they provide the . . .

     

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