Cytochrome p450 enzymes, drug transporters and their role in pharmacokinetic drug-drug interactions of xenobiotics: a comprehensive review

HIGHLIGHTS

  • who: Srinivas M and colleagues from the 00076, India have published the article: Cytochrome P450 Enzymes, Drug Transporters and their Role in Pharmacokinetic Drug-Drug Interactions of Xenobiotics: A Comprehensive Review, in the Journal: (JOURNAL)

SUMMARY

    Modification of a patient's clinical response to the administered drug by the co-administration of another drug is defined as a Drug-Drug Interaction (DDI). When the authors observe the alterations in drug disposition mainly via induction or inhibition of transporters or metabolic enzymes and drug transporters involved in drug absorption, distribution, metabolism or excretion, those . . .

     

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