Cytokine adsorber use during dcd heart perfusion counteracts coronary microvascular dysfunction

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SUMMARY

    Coronary microvascular dysfunction (CMVD {XE "MVD" "Coronary Microvascular Dysfunction"}) in cardiac allografts is associated with a higher likelihood of death, graft failure, or allograft vasculopathy after heart transplantation. Some transplant centers have established heart transplantation programs with hearts harvested from donors after circulatory death (DCD{XE "DCD" "Donation after Circulatory Death"}). DCD hearts must withstand a warm ischemic period followed by reperfusion during transportation by normothermic blood perfusion (BP{XE "BP" "Blood Perfusion"}) with blood collected from the deceased donor. Considering this, the authors investigated the effect of cytokine adsorption during blood perfusion of . . .

     

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