HIGHLIGHTS
- who: Adam R. Lefferts from the China Agricultural University, China have published the paper: Cytokine competent gut-joint migratory T Cells contribute to inflammation in the joint, in the Journal: (JOURNAL)
- what: The authors demonstrate gut-joint trafficking of colon IELs. The authors show that treatment with broad spectrum antibiotics reduces the number and pro-inflammatory potential of peripheral IELs, and results in a significant reduction in joint disease in the TNFDARE/+ model. The authors propose a model in which IELs are recruited to the gut in response to the detection of microbial products . While . . .
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