HIGHLIGHTS
- What: The aim of this work is to explore the role of cytoplasmic recycling of rcDNA-containing capsids in the hepatitis B virus (HBV) infection. Incorporating the effects of cure rate of infected hepatocytes, Wang et_al extended the model proposed by Min et_al . Considering the impacts of antibodies and CTLs, Danane et_al extended the model proposed by Manna and Chakrabraty , including immune_response of CTLs and examined role of optimal therapy in controlling viral_replication. In this study, an improved mathematical model incorporating the recycling effects of HBV capsids is proposed for the first time.
- Who: Mathematics . . .
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