HIGHLIGHTS
- who: Cynthia A. Leifer from the (UNIVERSITY) have published the research: Cytoplasmic Targeting Motifs Control Localization of Toll-like Receptor 9*, in the Journal: (JOURNAL) of November/17,/2006
- what: TLR9, the focus of the current study, responds to bacterial and viral DNA as well as synthetic oligodeoxynucleotides that contain unmethylated CpG dinucleotides in specific sequence con- * This NOVEMBER 17, 2006. The authors hypothesized that TLR9 contains specific motifs that control localization and trafficking. The authors focused on molecular structures contained in the cytoplasmic tail that dictate intracellular localization. The studies shown in Fig 1 . . .
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