Cytoskeletal anchorage of different dsg3 pools revealed by combination of hybrid sted/smfs-afm

HIGHLIGHTS

  • who: Michael Fuchs from the Munich, Germany University of Basel, Basel, Switzerland have published the research work: Cytoskeletal anchorage of different Dsg3 pools revealed by combination of hybrid STED/SMFS-AFM, in the Journal: (JOURNAL)
  • what: The authors describe a method to simultaneously characterize the actin organization and probe the single molecule binding properties of a desmosomal cadherin in correlation with the actin cytoskeleton. The authors showed that the STED/SMFS-AFM technique is applicable on living murine keratinocytes. This experiment demonstrated the existence of two different anchored Dsg3 pools and showed that both pools . . .

     

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