Cytosolic dna sensors and glial responses to endogenous dna

HIGHLIGHTS

• who: Alexander J. Suptela and Ian Marriott from the Yale University, United States have published the research: Cytosolic DNA sensors and glial responses to endogenous DNA, in the Journal: (JOURNAL)
• what: Interestingly, in this study, fragments of mtDNA were shown to be released in exosomes that were capable of initiating further inflammatory responses in nau00efve epithelial_cells . It is important to note that most of this work has been performed in keratinocytes and it remains to be determined whether such mechanisms exist in resident CNS cell type.
• future: Since the work of Mackenzie et . . .
  

   

  

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