HIGHLIGHTS
- who: Wei Huang from the Department of Critical Care Medicine, Nanfang, Medical University, Guangzhou, China, The First have published the research: Cytosolic p53 Inhibits Parkin-Mediated Mitophagy and Promotes Acute Liver Injury Induced by Heat Stroke, in the Journal: (JOURNAL)
- what: The aim of this study was to explore the involvement and regulation of mitophagy in HS-ALI. The authors provide additional mechanistic evidence that Parkin-mediated mitophagy was activated in hepatocytes exposed to HS-ALI, as illustrated by Parkin deletion, Mdivi-1, and 3-MA treatment. The study shows that p53 has a previously . . .
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