Cytotoxic effects of darinaparsin, a novel organic arsenical, against human leukemia cells

HIGHLIGHTS

  • who: Bo Yuan and colleagues from the Laboratory of Pharmacology, Graduate School of Pharmaceutical, Josai University, Sakado, Japan have published the research: Cytotoxic Effects of Darinaparsin, a Novel Organic Arsenical, against Human Leukemia Cells, in the Journal: (JOURNAL)
  • what: After exposure of NB4 cells to various concentrations of darinaparsin (0.3, 1, 2 u00b5M) for 24 h, annexin V/PI analysis was conducted to explore whether apoptosis and/or necrosis contributed to the cytotoxic effects of darinaparsin.
  • future: Collectively these findings suggest that the generality of the mechanism underlying the effects of darinaparsin . . .

     

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