Cytotoxicity-related effects of imidazolium and chlorinated bispyridinium oximes in sh-sy5y cells

HIGHLIGHTS

  • who: Arh Hig Rada Toksikol et al. from the InstitutUniversity of have published the research work: Cytotoxicity-related effects of imidazolium and chlorinated bispyridinium oximes in SH-SY5Y cells, in the Journal: (JOURNAL)
  • what: This study shows that the oximes interact with membrane acetylcholine receptors (AChRs), which include muscarinic (GPCR) and nicotinic (ionotorpic) receptors to block the release of iCa2+.
  • how: In silico target prediction For target prediction in silico the authors used the online SwissTargetPredicition web tool (Swiss Institute of Bioinformatics Lausanne Switzerland) which can predict the most probable target proteins of . . .

     

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