Daidzein and equol: ex vivo and in silico approaches targeting cox-2, inos, and the canonical inflammasome signaling pathway

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• What: This study shows that LPS up-regulates the NLRP3 protein expression in murine peritoneal macrophages, an effect inhibited by DZ and S-EQ treatments. Deepening the investigations for human purposes is necessary, considering all factors involved in the pharmacokinetic process and its biological factors, mainly biotransformation ones.
• Who: Yazmín K. Márquez-Flores and colleagues from the Departamento Farmacia, Escuela Nacional Ciencias Biológicas, Campus Zacatenco, Instituto Politécnico Departamento Química Farmacéutica Orgánica, Facultad Farmacia, Campus Cartuja, Universidad Granada, Granada, Spain have published the Article: Daidzein and Equol: Ex Vivo . . .
  

   

  

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