Dc-sign neck domain is a ph-sensor controlling oligomerization

HIGHLIGHTS

• who: Georges Tabarani from the (UNIVERSITY) have published the article: DC-SIGN Neck Domain Is a pH-sensor Controlling Oligomerization, in the Journal: (JOURNAL) of March/17,/2009
• what: Structural Organization of the Neck Domain-In this work the authors report for the first time the recombinant production of the neck domain depleted of its C-terminal CRD. Using SEC, the authors show that the whole neck domain in a slightly alkaline solution at a few micromolar concentration is present in two co-existing oligomeric states, the higher order one in large excess with respect . . .
  

   

  

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