Ddx39b drives colorectal cancer progression by promoting the stability and nuclear translocation of pkm2

HIGHLIGHTS

• who: Gang Zhao from the Animal experiments All animal experiments were approved by the Institutional Animal Care and Use Committee (IACUC) of West China Hospital Sichuan University4-to, week-old female athymic nude mice (BALB/ cJGpt-Foxn1nu/Gpt) were obtained from Gempharmatech Co [, ]. Ltd., Jiangsu, China. All mice were fed standard rodent forage and maintained under specific-pathogen-free (SPF) conditions at an ambient temperature of , u00b0C and , h/, h light/dark cycle. For the subcutaneous tumor model, the indicated CRC cells (, u00d7 , cells in , u03bcL PBS per mouse) were subcutaneously injected into the dorsal flanks of . . .
  

   

  

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