Ddx56 inhibits prv replication through regulation of ifn-β signaling pathway by targeting cgas

HIGHLIGHTS

• who: Ruofei Feng from the Wuhan University, China have published the article: DDX56 inhibits PRV replication through regulation of IFN-β signaling pathway by targeting cGAS, in the Journal: (JOURNAL)
• what: The authors demonstrate that DDX56 overexpression significantly reduced the replication of PRV infection, whereas DDX56 knockdown increased viral growth. The study examined how DDX56 affected cGAS-STING-TBK1, since this axis is crucial for host defense against DNA viruses (Kato et_al, 2017).
• how: Showed that DDX56 expression was decreased significantly in the siRNA transfection group as shown in Figure 2A. Showed that DDX56 . . .
  

   

  

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