Deacetylation of hsd17b10 by sirt3 regulates cell growth and cell resistance under oxidative and starvation stresses

HIGHLIGHTS

  • who: Lu Liu from the (UNIVERSITY) have published the Article: Deacetylation of HSD17B10 by SIRT3 regulates cell growth and cell resistance under oxidative and starvation stresses, in the Journal: (JOURNAL)
  • what: The authors show that HSD17B10 is deacetylated by SIRT3, and its function is regulated by its acetylation levels. The study demonstrated that acetylation of HSD17B10 regulates its functions and results in a change of cellular phenotype.
  • how: The results showed that GST-SIRT3 pulled down HSD17B10 (Fig 1e) and GSTHSD17B10 pulled down SIRT3 (Fig 1f). The result showed that K52 K53 K99 . . .

     

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