Debating the future of sickle cell disease curative therapy: haploidentical hematopoietic stem cell transplantation vs. gene therapy

HIGHLIGHTS

  • who: Adetola A. Kassim and Alexis Leonard from the Department of Medicine, Division of Hematology/Oncology, Vanderbilt Meharry Sickle Cell Center of Excellence, Vanderbilt University School of Medicine, Nashville, TN, USA have published the Article: Debating the Future of Sickle Cell Disease Curative Therapy: Haploidentical Hematopoietic Stem Cell Transplantation vs. Gene Therapy, in the Journal: (JOURNAL)
  • what: This approach for NMA haplo-BMT was developed to increase donor availability, minimize GvHD, and reduce toxicity.
  • future: This has allowed for the extension of this curative approach to individuals with severe SCD (pediatric and adults . . .

     

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