Deciphering how early life adiposity influences breast cancer risk using mendelian randomization

HIGHLIGHTS

  • who: Marina Vabistsevits from the UK UK UK UK UK UK UK have published the research work: Deciphering how early life adiposity influences breast cancer risk using Mendelian randomization, in the Journal: (JOURNAL)
  • what: Using a Mendelian randomization framework, the authors investigate 18 hypothesised mediators of the protective effect of childhood adiposity on later-life breast cancer, including hormonal, reproductive, physical, and glycaemic traits. It is plausible, however, that several related traits could collectively mediate the effect when analysed together, and this work provides a compelling foundation for investigating other mediating pathways in future studies . . .

     

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