Deciphering the molecular basis of ferroportin resistance to hepcidin: structure/function analysis of rare slc40a1 missense mutations found in suspected hemochromatosis type 4 patients

HIGHLIGHTS

• who: M. Le Tertre et al. from the Camille-Desmoulins, Brest, France have published the Article: Deciphering the molecular basis of ferroportin resistance to hepcidin: Structure/function analysis of rare SLC40A1 missense mutations found in suspected hemochromatosis type 4 patients, in the Journal: (JOURNAL)
• what: The authors propose strategy that not limited to structure analysis but integrates information from different sources including human disease-associated and functional in vitro assays. Based on structural and mutational analyses, the authors aim to:. get insight into the interaction of hepcidin with ferroportin; characterize sequence invariants that may play . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or E-mail:

  If you don't have an account, you can create one here.