HIGHLIGHTS
- who: Top from the Spain Molecular Oncology, Institute of Biomedical Investigation University Hospital ", de Octubre", Madrid, Spain have published the Article: Deciphering the role of nuclear and cytoplasmic IKK a in skin, in the Journal: (JOURNAL)
- how: The models of transgenic mice show that regardless of its subcellular localization in keratinocytes IKKα plays a protumoral role in skin cancer development and progression although by different mechanisms.
SUMMARY
Oncotarget layer of the epidermis and in the outer root sheath of hair follicles. The C -and-N-IKKα transgenic mice provide an excellent . . .
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