Decitabine improves mms-induced retinal photoreceptor cell damage by targeting dnmt3a and dnmt3b

HIGHLIGHTS

  • who: ufeffYanliufeff ufeffJiufeff et al. from the of Alabama at Birmingham, United States have published the article: Decitabine improves MMS-induced retinal photoreceptor cell damage by targeting DNMT3A and DNMT3B, in the Journal: (JOURNAL) of 10/01/2023
  • what: The authors aimed to explore the relationship between DNA methylation and DNA damage response in dying photoreceptors of RP.
  • how: In this study 5-aza-dC was applied to the eye before MMS treatment. Consistent with previous findings (Chen et_al 2020) the preliminary results showed that 5-aza-dC (2 u03bcM 1 u03bcl) intravitreal . . .

     

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