Decoding the pathogenesis of diamond-blackfan anemia using single-cell rna-seq

HIGHLIGHTS

  • who: Bingrui Wang from the (UNIVERSITY) have published the Article: Decoding the pathogenesis of Diamond-Blackfan anemia using single-cell RNA-seq, in the Journal: (JOURNAL)
  • what: The authors analyzed the transcriptomes of single purified erythroid progenitors isolated from the bone marrow of DBA patients. One additional limitation faced by this study was that, due to the young age of the patients when BM samples were collected (median 15 months old), it is difficult to obtain BM cells from age-matched controls and harvest sufficient erythroid progenitors for proteomic study.
  • how: To probe . . .

     

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