Decrease in the expression of muscle-specific mirnas, mir-133a and mir-1, in myoblasts with replicative senescence

HIGHLIGHTS

• who: Kaori Shintani-Ishida and colleagues from the Department of Forensic Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan have published the research work: Decrease in the expression of muscle-specific miRNAs, miR-133a and miR-1, in myoblasts with replicative senescence, in the Journal: PLOS ONE of 29/Dec/2022
• what: The authors determined whether miR-1 and miR-133a expression in myoblasts is altered with cellular senescence and involved in senescence-impaired myogenic differentiation.
• how: The study was carried out in compliance with the ARRIVE guidelines . . .
  

   

  

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