Decreased but diverse activity of cortical and thalamic neurons in consciousness-impairing rodent absence seizures

HIGHLIGHTS

  • who: Cian McCafferty from the Animals Experiments were carried out under approval by the Yale University Office of Animal Research SupportAll experiments were performed with Genetic Absence Epilepsy Rats from Strasbourg (GAERS), an established polygenic rat model of absence seizures88, between , and , months of age. Female animals were used because their smaller adult body size was conducive to the restricted bore size for MRI experiments. Animals had access to food and water ad libitum unless otherwise noted, and were kept on a, :, h light:dark cycle. Animals were group-housed prior to surgery and single-housed thereafter . . .

     

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