HIGHLIGHTS
- who: Cécile Pagan from the (UNIVERSITY) have published the Article: Decreased phenol sulfotransferase activities associated with hyperserotonemia in autism spectrum disorders, in the Journal: (JOURNAL) of 22/09/2010
- what: The authors report a deficient activity of both PST isoforms (M and P) in platelets from individuals with ASD (35% and 78% of patients respectively) confirmed in autoptic tissues (9 pineal gland samples from individuals with ASD-an important source of serotonin). The study proposes for the first time a compelling mechanism for hyperserotonemia in a context of global impairment of sulfation metabolism in . . .
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