Decreased plasma levels of pdgf-bb, vegf-a, and hif-2α in preterm infants after ibuprofen treatment

HIGHLIGHTS

  • who: Xueyu Chen and Chuanzhong Yang from the University of Oulu, Finland have published the Article: Decreased plasma levels of PDGF-BB, VEGF-A, and HIF-2u03b1 in preterm infants after ibuprofen treatment, in the Journal: (JOURNAL)
  • what: This study investigated the change of angiogenic factors after ibuprofen treatment in preterm infants.

SUMMARY

    Ibuprofen is one of the most common non-steroidal anti-inflammatory drugs used to close patent ductus arteriosus (PDA) in preterm infants. PDA is associated with bronchopulmonary dysplasia (BPD), while PDA closure by ibuprofen did not reduce the . . .

     

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