Decreased sirt1 activity is involved in the acute injury response of chondrocytes to ex vivo injurious mechanical overload

HIGHLIGHTS

• who: Sonali Karnik and collaborators from the Department of and Energy Engineering, Indiana University-Purdue University Indianapolis have published the research work: Decreased SIRT1 Activity Is Involved in the Acute Injury Response of Chondrocytes to Ex Vivo Injurious Mechanical Overload, in the Journal: (JOURNAL)
• what: In this study alterations to SIRT1 activity in bovine articular cartilage explants were evaluated in the 24 h following a overload and the effect of pharmacological SIRT1 activator SRT1720 on acute chondrocyte injury was assessed.
• how: Other data were analyzed with one- or two-way ANOVA as appropriate . . .
  

   

  

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