Dedifferentiation maintains melanocyte stem cells in a dynamic niche

HIGHLIGHTS

  • who: Qi Sun from the (UNIVERSITY) have published the research work: Dedifferentiation maintains melanocyte stem cells in a dynamic niche, in the Journal: (JOURNAL) of 16/03/2023
  • what: The authors show that most McSCs toggle between transit-amplifying and stem_cell states for both self-renewal and generation of mature progeny, a mechanism fundamentally distinct from those of other selfrenewing systems. The authors focused on a late-pigmentation gene, Oca2 (refs.

SUMMARY

    The authors show that most McSCs toggle between transit-amplifying and stem_cell states for both self-renewal and generation . . .

     

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