Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of european and african ancestries

HIGHLIGHTS

• who: Seyedeh M. Zekavat from the (UNIVERSITY) have published the research work: Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS of 04/07/2018
• what: Using a new imputation model to estimate KIV2-CN, the authors show that distinct LPA variant classes differentially influence clinical and subclinical atherosclerosis. Using a comprehensive genetic instrument that separately imputes apo(a) isoform, the authors show that knowledge of LPA genotypes can better inform incident cardiovascular disease risk prediction than just knowledge of Lp . . .
  

   

  

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