Deep mutational scanning: a versatile tool in systematically mapping genotypes to phenotypes

HIGHLIGHTS

  • who: January and colleagues from the Medical College of Wisconsin, United States Zhejiang University-University of Edinburgh Institute, Zhejiang University, Haining, Zhejiang, China have published the research: Deep mutational scanning: A versatile tool in systematically mapping genotypes to phenotypes, in the Journal: (JOURNAL)
  • what: Compared to the error-prone PCR, it is more costly but can generate a customized library with fewer For DMS studies aimed at endogenous genetic loci, CRISPR-based technologies (Doudna and Charpentier, 2014; Rees and Liu, 2018) are used. The motivation is to guide the readers on selecting the most appropriate . . .

     

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