Deep whole genome sequencing identifies recurrent genomic alterations in commonly used breast cancer cell lines and patient-derived xenograft models

HIGHLIGHTS

• who: Niantao Deng from the (UNIVERSITY) have published the Article: Deep whole genome sequencing identifies recurrent genomic alterations in commonly used breast cancer cell lines and patient-derived xenograft models, in the Journal: (JOURNAL)
• what: The authors performed deep WGS to provide a comprehensive resource of genomic events of these important BCCLs and PDX models. A substantial proportion (138/478) of the CNVs identified in this study but not in COSMIC are reported in Ben-David et_al using shallow WGS, suggesting the array-based method missed a lot of CNVs due to poor coverage. The . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.