Defective hematopoietic differentiation of immune aplastic anemia patient-derived ipscs

HIGHLIGHTS

  • who: Maria Florencia Tellechea from the treatment with h/rATG+CSA reaching partial or complete responseThe patients had normal telomere length (TL) for their ages in white blood cells (WBCs), and no pathogenic variants in , bone marrow syndromes related-genes (Supplementary Table, ). We also included control samples from three healthy donors have published the article: Defective hematopoietic differentiation of immune aplastic anemia patient-derived iPSCs, in the Journal: (JOURNAL) of 28/09/2021
  • what: The study shows that iPSCs are a reliable platform to model immune AA and adequately recapitulate the clinical phenotypes. Based on . . .

     

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