Defective monocyte-derived macrophage phagocytosis is associated with exacerbation frequency in copd

HIGHLIGHTS

  • who: R. Singh from the (UNIVERSITY) have published the research work: Defective monocyte-derived macrophage phagocytosis is associated with exacerbation frequency in COPD, in the Journal: (JOURNAL)
  • what: This study investigated the association between phagocytosis and frequency LABC and clinical parameters. In the study , only macrophages from COPD patients were studied, and all patients had considerable exposure to tobacco smoke with a median pack year history of 50. The study shows that defective COPD macrophage phagocytosis of H. influenzae is associated with increased exacerbation frequency, likely a result of an intrinsic defect within the macrophage . . .

     

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