Defects in g-actin incorporation into filaments in myoblasts derived from dysferlinopathy patients are restored by dysferlin c2 domains

HIGHLIGHTS

  • who: Ximena Báez-Matus et al. from the Centro Interdisciplinario de Neurociencia de Valparaíso, Facultad de Ciencias, Universidad de Valparaíso have published the research work: Defects in G-Actin Incorporation into Filaments in Myoblasts Derived from Dysferlinopathy Patients Are Restored by Dysferlin C2 Domains, in the Journal: (JOURNAL)
  • how: Since the study of Therrien et_al was carried out with isolated C2 domains it did not consider potential cooperative effects between tandem C2 domains as reported for synaptotagmin-1 C2 domains for its association to PI(45)P2 .
  • future: Studies are . . .

     

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