Defects in the nua4 acetyltransferase complex increase stability of the ribosomal rna gene and extend replicative lifespan

HIGHLIGHTS

• who: Genes Genet. Syst. ( and collaborators from the Institute for Quantitative Biosciences, The University of Tokyo, Yayoi, Bunkyo-ku, Tokyo, Japan have published the article: Defects in the NuA4 acetyltransferase complex increase stability of the ribosomal RNA gene and extend replicative lifespan, in the Journal: (JOURNAL)
• what: The authors tested rDNA stability using PFGE and ERC stress, underscoring that the rDNA is one of the most unstable regions in nature, the authors propose that an accumurDNA lation of rDNA damage determines replicative lifespan (Kobayashi, 2008).

SUMMARY

Genomic DNA was prepared in . . .

 



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