Defining the skeletal myogenic lineage in human pluripotent stem cell-derived teratomas

HIGHLIGHTS

• who: Matthew P. Pappas et al. from the Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA have published the Article: Defining the Skeletal Myogenic Lineage in Human Pluripotent Stem Cell-Derived Teratomas, in the Journal: Cells 2022, 11, 1589. of /2022/
• what: In the current study, the authors compared the trajectories of skeletal myogenic progenitor development towards myoblasts vs. muscle stem_cells and discovered that TGFu03b2 and Notch signaling might be important in this bifurcation process .
• how: The single-cell RNA seq dataset was analyzed using the R package Seurat . These results indicated . . .
  

   

  

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