Degradation of collagen i by activated c1s in periodontal ehlers-danlos syndrome

HIGHLIGHTS

• who: Albert Amberger and colleagues from the University of Gdanu0301sk and Medical University of Gdanu0301sk, Poland have published the research: Degradation of collagen I by activated C1s in periodontal Ehlers-Danlos Syndrome, in the Journal: (JOURNAL)
• what: The experiments showed that in pEDS fibroblasts, a considerable portion of intracellular procollagen I is cleaved by aC1s.

SUMMARY

Pathogenesis of pEDS thus differs from the other EDS types, which are usually due to a primary disturbance of extracellular matrix proteins, mostly involving collagens or collagen-modifying enzymes. The C1r CUB1 and CUB2 domains . . .

 



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