Deguelin attenuates non-small-cell lung cancer cell metastasis by upregulating pten/klf4/emt signaling pathway

HIGHLIGHTS

  • who: Guohua Lu and collaborators from the Department of Respiratory Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China have published the paper: Deguelin Attenuates Non-Small-Cell Lung Cancer Cell Metastasis by Upregulating PTEN/KLF4/EMT Signaling Pathway, in the Journal: Disease Markers of 21/05/2022
  • what: Deguelin effectively promoted the expression of PTEN and KLF4 in NSCLC cells in_vitro, and upregulated PTEN could increase the expression of KLF4 to suppress the EMT to further attenuate the invasion and migration of NSCLC cells.
  • how: Together these results indicated . . .

     

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