Dehydroepiandrosterone enhances decidualization in women of advanced reproductive age

HIGHLIGHTS

  • who: Douglas A. Gibson Ph.D. from the Centre University of United Kingdom have published the research work: Dehydroepiandrosterone enhances decidualization in women of advanced reproductive age, in the Journal: (JOURNAL) of August/29,/2017
  • what: The authors provide the first evidence that DHEA can act as a prohormone to increase intracrine androgen production in hESFs derived from normal endometrium during decidualization. The authors demonstrate that the capacity for a robust decidualization response is retained in women of advanced reproductive age and can be enhanced by increasing availability of the androgen precursor DHEA. The authors . . .

     

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