Delayed drug hypersensitivity reactions: molecular recognition, genetic susceptibility, and immune mediators

HIGHLIGHTS

  • who: Mu-Tzu Chu and colleagues from the Gung Memorial Hospital, Linkou Branch, Taoyuan, Taiwan University of British Columbia, Vancouver, BC V T , Canada have published the Article: Delayed Drug Hypersensitivity Reactions: Molecular Recognition, Genetic Susceptibility, and Immune Mediators, in the Journal: Biomedicines 2023, 11, 177. of /2023/
  • what: This model has been suggested by studies on abacavir hypersensitivity .
  • how: The authors carried out a prospective study and showed that the genetic screening of HLA-B*1502 before CBZ administration prevented the occurrence of CBZ-induced SJS/TEN .

SUMMARY

     

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