Delayed mesolimbic system alteration in a developmental animal model of schizophrenia

HIGHLIGHTS

  • who: Yukiori, Goto and Patricio, O'Donnell from the Center for Neuropharmacology have published the article: Delayed Mesolimbic System Alteration in a Developmental Animal Model of Schizophrenia, in the Journal: (JOURNAL) of October/15,/2002
  • what: One should be aware, however, that this model has limitations.
  • how: The authors explored whether the dopamine projection to the nucleus accumbens becomes functionally altered in these animals. To assess the developmental nature of the changes observed the results were compared with sham and neonatally lesioned animals tested before puberty and with animals that received a lesion . . .

     

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