Deletion of a conserved gata2 enhancer impairs haemogenic endothelium programming and adult zebrafish haematopoiesis

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  • who: Tomasz Dobrzycki from the Radcliffe Hospital University of Oxford, Oxford , DS, UK have published the Article: Deletion of a conserved Gata2 enhancer impairs haemogenic endothelium programming and adult Zebrafish haematopoiesis, in the Journal: (JOURNAL) of 25/04/2019
  • what: The authors show that the gata2a locus contains a conserved enhancer in its 4th intron corresponding to the described +9.5 enhancer in the mouse Gata2 locus18 19. To avoid any confounding effects in the analysis the authors compared wild-type to gata2aΔi4/Δi4 mutants without overt signs of infection. The authors propose a . . .

     

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