Deletion of classical transient receptor potential 1, 3 and 6 alters pulmonary vasoconstriction in chronic hypoxia-induced pulmonary hypertension in mice

HIGHLIGHTS

• who: . and colleagues from the The University of Chicago, United States have published the research work: Deletion of classical transient receptor potential 1, 3 and 6 alters pulmonary vasoconstriction in chronic hypoxia-induced pulmonary hypertension in mice, in the Journal: (JOURNAL)
• what: The authors demonstrate that deletion of TRPC1, 3 and 6 alters (hypoxic) pulmonary vasoconstriction, which is associated with a partial protection against CHPH.
• how: The partial protection against CHPH in TRPC1/3/6-/- mice is not driven by an altered vascular remodeling All data are given as mean u00b1 SEM.
 



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