Deletion of hp1γ in cardiac myocytes affects h4k20me3 levels but does not impact cardiac growth

HIGHLIGHTS

• who: Kyohei Oyama from the The HP1γfl mouse was generated from the HP1γhypo/hypo [23] by excision of the FRT-NeO-FRT cassette after crossing to a FLPe mouse [24]The resulting HP1γfl mouse was crossed to the Nkx2.5-Cre mouse [25] to achieve cardiac-specific HP1γ KO. Litter mates were used as controls for this study. Mice were housed in a temperature-controlled environment with , h light/dark cycles where they received food and water ad libitum. All protocols concerning the use of animals were approved by the Institutional Animal Care and . . .
  

   

  

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