Deletion of pomt2 in zebrafish causes degeneration of photoreceptors

HIGHLIGHTS

  • who: Yu Liu and collaborators from the Center for Vision Research, Departments of Neuroscience and Physiology and of Ophthalmology and Visual, Medical University, Syracuse, NY, USA have published the research work: Deletion of POMT2 in Zebrafish Causes Degeneration of Photoreceptors, in the Journal: (JOURNAL)
  • what: The authors show that deletion of POMT2 in zebrafish results in a loss of matriglycan, diminished expression and mis-localization of EYS, and photoreceptor degeneration.
  • how: These data indicated that there was a loss of cone photoreceptors in pomt2 mutant zebrafish at 6-mpf. Given that there is . . .

     

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