Deletion of the accramycin pathway-specific regulatory gene accj activates the production of unrelated polyketide metabolites

HIGHLIGHTS

• who: Fleurdeliz Maglangit from the DepartmentUniversity of have published the research work: Deletion of the accramycin pathway-specific regulatory gene accJ activates the production of unrelated polyketide metabolites, in the Journal: (JOURNAL)
• what: The authors report the inactivation of the accramycin pathway-specific regulatory_gene, accJ in Streptomyces sp.
• how: The mass spectrometric data were obtained on Linear Trap Quadropole (LTQ) Orbitrap coupled to an Agilent 1260 Infinity HPLC system consisting of a quaternary HPLC pump column compartment cooled autosampler compartment and diode array UV-Vis detector.

SUMMARY

The manipulation . . .

 



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